[PDF.42fu] PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy)
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PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy)
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| #4373288 in Books | 2009-10-23 | Original language:English | PDF # 1 | 9.30 x.90 x6.30l,1.85 | File type: PDF | 290 pages||||From the reviews:“The volume is dedicated to the recent advances on PEGylation and PEGylated compunds. It represents an excellent update in the evolution of this field, from nanoscience to clinical applications. The book provides an excellent update in
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-ol...
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